Spatiotemporal landscape of murine thymus reveals B cell-enriched inflammatory niche in thymus aging[Stereo-seq]
IDSTT0000120(Source: STOmics DB)
STOmics technology:BGI Stereomics Stereo-Seq
Organism(s):
Mus musculus
Data type:Spatial transcriptomics
Sample scope:Monoisolate
Summary:Age-related thymic involution is closely associated with immunosenescence, inflammaging, and autoimmune disorders. However, the spatiotemporal features of developmental and aging thymus remain unknown. Here we constructed a spatiotemporal landscape of murine thymus from newborns to the aged using the self-developed spatial enhanced resolution omics-sequencing (Stereo-seq) and single-cell RNA sequencing (scRNA-seq).[Stereo-seq]
Contributor(s):Yang ZongHeng.
Publication(s):
  • Yang ZongHeng. Spatiotemporal landscape of murine thymus reveals B cell-enriched inflammatory niche in thymus aging[Stereo-seq].
Submitter:刘怡(Yi Liu),BGI
Release date:2024-10-30
Updated:2024-11-22
Statistics:
  • Sample: 4
  • Tissue Section: 9
Datasize:2.24GB
Spatial Gene Expression
ProjectSampleTissue SectionOrganismFiles