HHSTA: Human Hippocampal Spatial Transcriptomic Atlas of Alzheimer's disease(Dataset ID: STDS0000380)

0
|
176
|
25
Summary
Visualization
Data
Catalog
Dataset information
Contributors
Accessions
How to cite
Dataset information
Summary:
The HHSTA database comprises 32 sections from the middle region of the hippocampus, obtained using Stereo-seq. From 16 samples, two biological replicates were collected per sample. In HHSTA, we present spatial maps illustrating cell distribution and gene expression for each section. This hippocampus atlas enables in-depth investigation into longstanding questions regarding the pathogenesis of Alzheimer's disease.
Overall design:
The Human Hippocampal Spatial Transcriptome Atlas of Alzheimer's Disease HHSTA is an interactive visualization that allows users to view and retrieve the spatial expression of individual genes in the human hippocampus between AD patients and controls. The Stereo-seq technology used by HHSTA, with sub-cellular resolution, provides extremely rich information for in-depth study of the pathogenesis of AD patients.
Platform:
DNBSEQ-T1 | DNBSEQ-T10
Tissues:
Brain
Organ parts:
Hippocampus
Sex:
Male | Female
Submission date: 2025-03-31Update date: 2025-03-31
Sample number: 33Section number: 33
DOI: To be continue
Contributors
hanlei
Accessions
CNSA project: CNP0005077
How to cite
  • Cite database of STOmicsDB:
    [1] Xu, Zhicheng et al. "STOmicsDB: a comprehensive database for spatial transcriptomics data sharing, analysis and visualization." Nucleic acids research vol. 52,D1 (2024): D1053-D1061. doi: 10.1093/nar/gkad933'
  • Cite visualization dataset:
    [2] hanlei. HHSTA: Human Hippocampal Spatial Transcriptomic Atlas of Alzheimer's disease[DS/OL]. STOmicsDB, 2025[2025-03-31]. https://db.cngb.org/stomics/datasets/STDS0000380/. doi: xxxxxx
    #Format: {contributors}. {title}[DS/OL]. STOmicsDB, {the year of submission data}[{submission data}]. {dataset link}. doi: {doi ID}
  • Cite original data article:
    Citation: Wang, P., Han, L., Wang, L., Tao, Q., Guo, Z., Luo, T., ... & Zhang, J. (2025). Molecular Pathways and Diagnosis in Spatially Resolved Alzheimer’s Hippocampal Atlas. Neuron. Advance online publication. https://doi.org/10.1016/j.neuron.2025.03.002