High spatial resolution imaging mass spectrometry and classical histology on a single tissue section.
Abstract
The work presented in this report describes and demonstrates a protocol for protein imaging analysis of biological tissue using MALDI IMS where histological staining and MS analysis are performed on the same tissue section. Spatial image resolution is shown at 35 µm for sagittal sections of the cerebellum from rat brain.
Keywords
MALDI
MeSH terms
Animals
Cerebellum
Female
Histocytochemistry
Histocytological Preparation Techniques
Male
Molecular Imaging
Nerve Tissue Proteins
Rats
Rats, Sprague-Dawley
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Authors
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