Exploring the mechanism of tumer microenvironment reconstruction in the process of breast cancer invasion
IDSTT0000067(Source: STOmics DB)
STOmics technology:BGI Stereomics Stereo-Seq
Organism(s):
Homo sapiens
Data type:Spatial transcriptomics
Sample scope:Multiisolate
Summary:Breast cancer is a leading cause of death that seriously threatens women's life and health. Tumor invasion is a crucial event in the progression of breast cancer. However, we still know little about the specific mechanisms of tumor invasion in breast cancer. In this study, we perform single-cell and spatial RNA-sequencing on tumor samples from normal, in situ and invasive regions to explore the specific cellular and molecular mechanisms of the dynamic tumor microenvironment reconstruction during tumor invasion, thus providing new targets for clinical diagnosis and treatment of breast cancer.
Contributor(s):Di Wang, Jingwen Guo, Guixiang Ye.
Publication(s):
  • Di Wang, Jingwen Guo, Guixiang Ye. Spatial transcriptomics track the evolutionary hierarchy and tumor microenvironment remodeling in breast cancer.
Submitter:郭靖文(Jingwen Guo),BGI
Release date:2025-12-20
Updated:2025-12-20
Statistics:
  • Sample: 9
  • Tissue Section: 9
Datasize:13.44GB
Spatial Gene Expression
ProjectSampleTissue SectionOrganismFiles