Single-cell and spatial transcriptomics reveal the mechanisms of bile duct injury in biliary atresia
IDSTT0000060(Source: STOmics DB)
STOmics technology:BGI Stereomics Stereo-Seq
Organism(s):
Homo sapiens
Data type:Raw sequence reads, Transcriptome or Gene expression, Spatial transcriptomics
Sample scope:Monoisolate
Summary:Biliary Atresia(BA) is a devastating pediatric cholangiopathy affecting the bile ducts of the liver. This research utilized spatial and single-cell transcriptomics to analyze the immune microenvironment of biliary atresia, revealing the mechanisms of bile duct injury that occur concurrently with inflammation and fibrosis.
Contributor(s):Dong Ma, Manhuan xiao, Sihan wu.
Publication(s):
  • Dong Ma, Manhuan xiao, Sihan wu. Single-cell and spatial transcriptomics reveal the mechanisms of bile duct injury in biliary atresia.
Submitter:马栋(DongMa),Sun Yat-Sen University
Release date:2025-12-05
Updated:2025-12-05
Statistics:
  • Sample: 4
  • Tissue Section: 4
  • Experiment: 10
  • Run: 146
Datasize:965.51GB
Sequencing Data
Spatial Gene Expression
ProjectSampleTissue SectionExperimentRunOrganismPlatformSequencing readsMask file