ARTISTA: Axolotl Regenerative Telencehpalon Interpretation via Spatiotemporal Transcriptomic Atlas(Dataset ID: STDS0000056)

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36,949
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37,241
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Genes: 30,178
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PMID: 36048929
Summary
Visualization
Data
Analysis results
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Dataset information
Summary:
Axolotl Regenerative Telencehpalon Interpretation via Spatiotemporal Transcriptomic Atlas (ARTISTA) is a spatially resolved transcriptomic data resource that provides visualization of gene expression across the regeneration and development stages of axolotl telencephalon at single cell resolution, aiming to provide a systematic dissection of the molecular events underlying neural regeneration in the axolotl brain, laying the foundation for further mechanistic studies. To comprehensively understand cellular dynamics occurred during axolotl brain regeneration and development, here, we carried out a series of spatial transcriptome analyses on serial sections along the rostral-caudal axis of 2 (3 sections), 5 (3 sections), 10 (3 sections), 15 (4 sections), 20 (3 sections), 30 and 60 days post injury (DPI) brain tissues after removal of a reproducible portion of dorsal pallium in left telencephalic hemisphere of 11 cm length axolotl. We also collected sections from developmental (stage 44, 54, and 57), juvenile, adult, and metamorphosed axolotl telencephalons. Based on this dataset, researchers can quickly explore the gene expression profiles of their interested cell types in spatial map across different regeneration and development stages of axolotl telencephalon.
Technology:
Stereo-Seq
Platform:
DNBSEQ-T1
Species:
Ambystoma mexicanum
Tissues:
Brain
Development stage:
Developmental stage 44,Developmental stage 54,Developmental stage 57,Juvenile,Adult,Metamorphosed an
Disease:
Injured brain
Submission date: 2021-08-01Update date: 2021-08-01
Sample number: 36Section number: 16
DOI: To be continue
Contributors
No results.
Accessions
Project ID: CNP0002068
database url: https://db.cngb.org/stomics/artista/
How to cite
  • Cite database of STOmicsDB:
    [1] Xu, Zhicheng et al. "STOmicsDB: a comprehensive database for spatial transcriptomics data sharing, analysis and visualization." Nucleic acids research vol. 52,D1 (2024): D1053-D1061. doi: 10.1093/nar/gkad933'
  • Cite visualization dataset:
    [2] xxxxxx. ARTISTA: Axolotl Regenerative Telencehpalon Interpretation via Spatiotemporal Transcriptomic Atlas[DS/OL]. STOmicsDB, 2021[2021-08-01]. https://db.cngb.org/stomics/datasets/STDS0000056/. doi: xxxxxx
    #Format: {contributors}. {title}[DS/OL]. STOmicsDB, {the year of submission data}[{submission data}]. {dataset link}. doi: {doi ID}
  • Cite original data article:
    Citation: Wei, Xiaoyu et al. “Single-cell Stereo-seq reveals induced progenitor cells involved in axolotl brain regeneration.” Science (New York, N.Y.) vol. 377,6610 (2022): eabp9444. doi:10.1126/science.abp9444