Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease(Dataset ID: STDS0000012)

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754
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4,704
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Spots: 15,062
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Genes: 22,701
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PMID: 33083725 (IF:5.8 Q1)
Summary
Visualization
Data
Analysis results
Sample
Catalog
Dataset information
Contributors
Accessions
How to cite
Dataset information
Summary:
This is the public data repository for the the work presented in Navarro and Croteau et al. iScience, 2020. https://doi.org/10.1016/j.isci.2020.101556 The repository contains 48 Spatial Tancriptomics (ST) sections (24 of the hippocampus and 24 of the olfactory bulb). The sections were obtained from an Alzheimer´s disease mouse model: 3xAD, 3xPB, 3xPB and WT For each section, we have deposited the following: - H&E file - Matrix of counts We also included the merged matrices of counts and meta files. The results of the analyses are also present (factor analysis clusters, DE analysis genes, pathways, etc...). License:CC BY 4.0(https://creativecommons.org/licenses/by/4.0/)
Technology:
Spatial Transcriptomics
Species:
Mus musculus
Tissues:
Brain
Organ parts:
Hippocampus,Olfactory bulb
Sex:
Male
Disease:
Alzheimer disease
Submission date: 2020-09-21Update date: 2020-09-21
Sample number: 24Section number: 48
DOI: To be continue
Contributors
Jose Fernandez Navarro
How to cite
  • Cite database of STOmicsDB:
    [1] Xu, Zhicheng et al. "STOmicsDB: a comprehensive database for spatial transcriptomics data sharing, analysis and visualization." Nucleic acids research vol. 52,D1 (2024): D1053-D1061. doi: 10.1093/nar/gkad933'
  • Cite visualization dataset:
    [2] Jose Fernandez Navarro. Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease[DS/OL]. STOmicsDB, 2020[2020-09-21]. https://db.cngb.org/stomics/datasets/STDS0000012/. doi: xxxxxx
    #Format: {contributors}. {title}[DS/OL]. STOmicsDB, {the year of submission data}[{submission data}]. {dataset link}. doi: {doi ID}
  • Cite original data article:
    Citation: Navarro, José Fernández et al. “Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease.” iScience vol. 23,10 101556. 15 Sep. 2020, doi:10.1016/j.isci.2020.101556