Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease
Dataset ID: STDS0000012
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PMID:33083725
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15,062 Spots
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22,701 Genes
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Summary:
This is the public data repository for the the work presented in Navarro and Croteau et al. iScience, 2020. https://doi.org/10.1016/j.isci.2020.101556 The repository contains 48 Spatial Tancriptomics (ST) sections (24 of the hippocampus and 24 of the olfactory bulb). The sections were obtained from an Alzheimer´s disease mouse model: 3xAD, 3xPB, 3xPB and WT For each section, we have deposited the following: - H&E file - Matrix of counts We also included the merged matrices of counts and meta files. The results of the analyses are also present (factor analysis clusters, DE analysis genes, pathways, etc...). License:CC BY 4.0(https://creativecommons.org/licenses/by/4.0/)
Technology:
Spatial Transcriptomics
Species:
Mus musculus
Tissues:
Brain
Organ parts:
Hippocampus, Olfactory bulb
Sex:
Male
Disease:
Alzheimer disease
Citation:
Navarro, José Fernández et al. “Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease.” iScience vol. 23,10 101556. 15 Sep. 2020, doi:10.1016/j.isci.2020.101556
Submission date: 2020-09-21Update date: 2020-09-21
Sample number: 24Section number: 48
Contributors
Jose Fernandez Navarro