The kidney-more than the sum of its cellular parts.
IF: 18.998
Cited by: 1


The kidney is a complex organ composed of a plethora of highly specialized cells that talk to each other. The tubuloglomerular feedback is a prototypical example of cell-cell interactions adapting glomerular filtration rate. With the advent of single-cell sequencing techniques, spatial transcriptomics, and bioinformatical cell-cell interaction analyses, we are now able to much better decipher the complex physiology and pathophysiology of these crosstalks, and identify new biomarkers as well as novel treatment options.


Spatial Transcriptomics

MeSH terms

Glomerular Filtration Rate
Blood Pressure
Cell Communication


Perco, Paul
Mayer, Gert