Single cell biology-a Keystone Symposia report.
IF: 6.499


Single cell biology has the potential to elucidate many critical biological processes and diseases, from development and regeneration to cancer. Single cell analyses are uncovering the molecular diversity of cells, revealing a clearer picture of the variation among and between different cell types. New techniques are beginning to unravel how differences in cell state-transcriptional, epigenetic, and other characteristics-can lead to different cell fates among genetically identical cells, which underlies complex processes such as embryonic development, drug resistance, response to injury, and cellular reprogramming. Single cell technologies also pose significant challenges relating to processing and analyzing vast amounts of data collected. To realize the potential of single cell technologies, new computational approaches are needed. On March 17-19, 2021, experts in single cell biology met virtually for the Keystone eSymposium "Single Cell Biology" to discuss advances both in single cell applications and technologies.


Spatial Transcriptomics
lineage tracing
single cell sequencing
spatial transcriptomics

MeSH terms

Cell Differentiation
Cell Lineage
Cellular Reprogramming
Congresses as Topic
Embryonic Development
Research Report
Single-Cell Analysis


Cable, Jennifer
Elowitz, Michael B
Domingos, Ana I
Habib, Naomi
Itzkovitz, Shalev
Hamidzada, Homaira
Balzer, Michael S
Yanai, Itai
Liberali, Prisca
Whited, Jessica
Streets, Aaron
Cai, Long
Stergachis, Andrew B
Hong, Clarice Kit Yee
Keren, Leeat
Guilliams, Martin
Alon, Uri
Shalek, Alex K
Hamel, Regan
Pfau, Sarah J
Raj, Arjun
Quake, Stephen R
Zhang, Nancy R
Fan, Jean
Trapnell, Cole
Wang, Bo
Greenwald, Noah F
Vento-Tormo, Roser
Santos, Silvia D M
Spencer, Sabrina L
Garcia, Hernan G
Arekatla, Geethika
Gaiti, Federico
Arbel-Goren, Rinat
Rulands, Steffen
Junker, Jan Philipp
Klein, Allon M
Morris, Samantha A
Murray, John I
Galloway, Kate E
Ratz, Michael
Romeike, Merrit