A Comparative Overview of Epigenomic Profiling Methods.
IF: 6.081
Cited by: 2


In the past decade, assays that profile different aspects of the epigenome have grown exponentially in number and variation. However, standard guidelines for researchers to choose between available tools depending on their needs are lacking. Here, we introduce a comprehensive collection of the most commonly used bulk and single-cell epigenomic assays and compare and contrast their strengths and weaknesses. We summarize some of the most important technical and experimental parameters that should be considered for making an appropriate decision when designing epigenomic experiments.


DNA methylation
assay comparison
chromatin profiles
epigenomic assays
multi-omics methods
single-cell epigenome profiling


Mehrmohamadi, Mahya
Sepehri, Mohammad Hossein
Nazer, Naghme
Norouzi, Mohammad Reza

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