See(quence) and ye shall find: higher-order genome folding in intact single cells.
Abstract
Payne et al. (2020) combine in situ imaging and ex situ sequencing via spatially resolved unique molecular barcodes to query higher-order genome folding patterns in intact single nuclei from mouse embryos and human fibroblasts.
Keywords
ISS
MeSH terms
Animals
Base Sequence
Genome
Mice
Authors
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