An atlas of the protein-coding genes in the human, pig, and mouse brain.
IF: 63.714
Cited by: 380


The brain, with its diverse physiology and intricate cellular organization, is the most complex organ of the mammalian body. To expand our basic understanding of the neurobiology of the brain and its diseases, we performed a comprehensive molecular dissection of 10 major brain regions and multiple subregions using a variety of transcriptomics methods and antibody-based mapping. This analysis was carried out in the human, pig, and mouse brain to allow the identification of regional expression profiles, as well as to study similarities and differences in expression levels between the three species. The resulting data have been made available in an open-access Brain Atlas resource, part of the Human Protein Atlas, to allow exploration and comparison of the expression of individual protein-coding genes in various parts of the mammalian brain.


Gene Expression
Spatial Transcriptomics

MeSH terms

Atlases as Topic
Datasets as Topic
Gene Expression Regulation
Mice, Inbred C57BL
Nerve Tissue Proteins
Organ Specificity
Species Specificity


Sjöstedt, Evelina
Zhong, Wen
Fagerberg, Linn
Karlsson, Max
Mitsios, Nicholas
Adori, Csaba
Oksvold, Per
Edfors, Fredrik
Limiszewska, Agnieszka
Hikmet, Feria
Huang, Jinrong
Du, Yutao
Lin, Lin
Dong, Zhanying
Yang, Ling
Liu, Xin
Jiang, Hui
Xu, Xun
Wang, Jian
Yang, Huanming
Bolund, Lars
Mardinoglu, Adil
Zhang, Cheng
von Feilitzen, Kalle
Lindskog, Cecilia
Pontén, Fredrik
Luo, Yonglun
Hökfelt, Tomas
Uhlén, Mathias
Mulder, Jan

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