SpatialDE: identification of spatially variable genes.
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IF: 47.990
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Cited by: 313
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Abstract

Technological advances have made it possible to measure spatially resolved gene expression at high throughput. However, methods to analyze these data are not established. Here we describe SpatialDE, a statistical test to identify genes with spatial patterns of expression variation from multiplexed imaging or spatial RNA-sequencing data. SpatialDE also implements 'automatic expression histology', a spatial gene-clustering approach that enables expression-based tissue histology.

Keywords

Seurat
Spatial Gene Expression

MeSH terms

Breast Neoplasms
Female
Gene Expression Regulation, Neoplastic
Humans
Models, Biological
Protein Transport
Single-Cell Analysis

Authors

Svensson, Valentine
Teichmann, Sarah A
Stegle, Oliver

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