Spatial multi-omics reveals vulnerabilities of radial glia-like cancer-initiating cells within distinct ecosystems of pediatric and adult malignant gliomas(Dataset ID: STDS0000206)

0
|
1,169
|
4,149
|
PMID: 36823172
Summary
Visualization
Data
Analysis results
Related
Sample
Catalog
Dataset information
Contributors
Accessions
How to cite
Dataset information
Summary:
We collected five DMG, five GBM (including two secondary GBM), and one peritumor samples from eleven patients requiring surgical resection. To establish an atlas for spatially-resolved gene expression, we performed short-read spatial transcriptomic sequencing on the tissue sections using the 10x Visium platform.
Overall design:
Here, we established a spatial atlas of H3K27M-DMG and GBM through short read spatial transcriptomics to reveal the niche-specific distribution and vulnerability of stem-like cells in H3K27M-DMG and GBM
Technology:
10x Visium
Platform:
Illumina HiSeq 2000
Species:
Homo sapiens(hg38)
Submission date: 2022-01-25Update date: 2023-03-14
Sample number: 11
DOI: To be continue
Contributors
Wang, Yuan,Huang, Zongyao,Ren, Yanming,Zhou, Lingling,Xiao, Peng,Song, Junwei,Chen, Lu,Ju, Yan,Zhang
Accessions
GEO Series Accessions: GSE194329
How to cite
  • Cite database of STOmicsDB:
    [1] Xu, Zhicheng et al. "STOmicsDB: a comprehensive database for spatial transcriptomics data sharing, analysis and visualization." Nucleic acids research vol. 52,D1 (2024): D1053-D1061. doi: 10.1093/nar/gkad933'
  • Cite visualization dataset:
    [2] Wang, Yuan,Huang, Zongyao,Ren, Yanming,Zhou, Lingling,Xiao, Peng,Song, Junwei,Chen, Lu,Ju, Yan,Zhang. Spatial multi-omics reveals vulnerabilities of radial glia-like cancer-initiating cells within distinct ecosystems of pediatric and adult malignant gliomas[DS/OL]. STOmicsDB, 2022[2022-01-25]. https://db.cngb.org/stomics/datasets/STDS0000206/. doi: xxxxxx
    #Format: {contributors}. {title}[DS/OL]. STOmicsDB, {the year of submission data}[{submission data}]. {dataset link}. doi: {doi ID}
  • Cite original data article:
    Citation: Ren, Yanming et al. “Spatial transcriptomics reveals niche-specific enrichment and vulnerabilities of radial glial stem-like cells in malignant gliomas.” Nature communications vol. 14,1 1028. 23 Feb. 2023, doi:10.1038/s41467-023-36707-6