Interleukin-17 governs hypoxic adaptation of injured epithelium [spatial transcriptomics](Dataset ID: STDS0000089)

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Spots: 3,909
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Catalog



Dataset information
Summary:
To define the gene signature and spatial architecture of the skin after injury, we performed spatial transcriptomics from mouse unwounded and wounded skin.
Overall design:
Wild type (unwounded, wounded) and GFP-KI (wounded) skin were fresh frozen and sectioned at 10um thickness onto spatial transcriptomics (ST) slides for mRNA capture, followed by library preparation and sequencing. The GFP-KI genotype disrupts the Rorc gene.
Technology:
10x Visium
Platform:
GPL24247
Species:
Mus musculus(mm10)
Tissues:
Skin
Disease:
Injured skin
Submission date: 2021-02-17Update date: 2021-02-22
DOI: To be continue

Contributors
Piotr Konieczny,Xing Yue,Ikjot Sidhu,Shruti Naik
Contact: Shruti.Naik@nyulangone.org

Accessions
GEO Series Accessions: GSE166948

How to cite
  • Cite database of STOmicsDB:
    [1] Xu, Zhicheng et al. "STOmicsDB: a comprehensive database for spatial transcriptomics data sharing, analysis and visualization." Nucleic acids research vol. 52,D1 (2024): D1053-D1061. doi: 10.1093/nar/gkad933'
  • Cite visualization dataset:
    [2] Piotr Konieczny,Xing Yue,Ikjot Sidhu,Shruti Naik. Interleukin-17 governs hypoxic adaptation of injured epithelium [spatial transcriptomics][DS/OL]. STOmicsDB, 2021[2021-02-17]. https://db.cngb.org/stomics/datasets/STDS0000089/. doi: xxxxxx
    #Format: {contributors}. {title}[DS/OL]. STOmicsDB, {the year of submission data}[{submission data}]. {dataset link}. doi: {doi ID}
  • Cite original data article:
    Citation: Konieczny, Piotr et al. “Interleukin-17 governs hypoxic adaptation of injured epithelium.” Science (New York, N.Y.) vol. 377,6602 (2022): eabg9302. doi:10.1126/science.abg9302