Lactuca graminifolia, the grassleaf lettuce is a North American species of wild lettuce. It grows in Mexico, Central America, Hispaniola, and the southern United States from Arizona to Florida, Virginia and the Carolinas.

Lactuca graminifolia is a biennial herb in the dandelion tribe within the daisy family growing from a taproot a height of up to 150 cm (5 feet). The top of the stem bears a multibranched inflorescence with many flower heads. Each head contains 15-20 blue or purple ray florets but no disc florets. The fruit is a brown achene.