CNGB Imputation Service
88,000,000
Reference Genomes Variants
CNGB Imputation Service
166
Registered Users
CNGB Imputation Service
1,022
Jobs

The safest way to impute genotypes

CNGB Imputation Service

Highly convenient

A new web-based service for imputation that greatly improves user experience and productivity.
CNGB Imputation Service

Secure and private

Protect the security and privacy of reference panel and users' data at the same time. You have full control about the service.
CNGB Imputation Service

Reference panel

Our sever offers genotype imputation from the 1000 Genomes (Phase 3 v5) reference panels with genome assembly GRCh37 (hg19) and GRCh38.

The easiest way to impute genotypes

CNGB Imputation Service
Upload your genotype files
CNGB Imputation Service
Select a reference panel
CNGB Imputation Service
Download the results

Imputation workflow

CNGB Imputation Service

Genotype imputation is a commonly used technique that exploits linkage disequilibrium (LD) to infer missing genotypes in genetic datasets, using a reference panel of subjects with complete observations on a more comprehensive set of SNPs.

News

A high-resolution haplotype-resolved Reference panel constructed from the China Kadoorie Biobank Study, published on 23 October 2023 in Nucleic Acids Research.
2023-10-23
The CNGB Imputation Service’s Reference panel has added the China Kadoorie Biobank (CKB).
2023-09-21
Redesigned user interface to improve user experience.
2021-10-10
Updated pipeline to v1.1.0. Currently, your CNGB Imputation pipeline will run on an SGX-based trusted execution environment.
2021-09-30
The CNGB Imputation Service v1.0.0 is online and available to signed-up users.
2021-09-01

How to cite

Yu, C., Lan, X., Tao, Y., Guo, Y., Sun, D., Qian, P., ... & Li, L. (2023). A high-resolution haplotype-resolved Reference panel constructed from the China Kadoorie Biobank Study. Nucleic Acids Research, 51(21), 11770-11782. https://doi.org/10.1093/nar/gkad779