PIEZO1 piezo type mechanosensitive ion channel component 1 [ Homo sapiens (human) ] - Gene - Data resources

9780

PIEZO1 piezo type mechanosensitive ion channel component 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 9780)

Symbol: PIEZO1

Full name: piezo type mechanosensitive ion channel component 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: DHS; ER; FAM38A; LMPH3; LMPHM6; Mib

Summary: The protein encoded by this gene is a mechanically-activated ion channel that links mechanical forces to biological signals. The encoded protein contains 36 transmembrane domains and functions as a homotetramer. Defects in this gene have been associated with dehydrated hereditary stomatocytosis. [provided by RefSeq, Jul 2015]

Expression: Ubiquitous expression in fat (RPKM 30.4), lung (RPKM 14.8) and 24 other tissues

Orthologs: mouse

Gene size: 69883bp

Exon count: 51