Piezo1 piezo-type mechanosensitive ion channel component 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 234839)
Source: NCBI Gene (ID 234839)
Symbol: Piezo1
Full name: piezo-type mechanosensitive ion channel component 1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 9630020g22; Fam38a; mKIAA0233
Summary: Enables identical protein binding activity and mechanosensitive cation channel activity. Involved in positive regulation of myotube differentiation. Acts upstream of or within cation transport; detection of mechanical stimulus; and regulation of membrane potential. Located in plasma membrane. Is expressed in several structures, including hemolymphoid system; liver; and lung. Human ortholog(s) of this gene implicated in dehydrated hereditary stomatocytosis 1 and hereditary lymphedema. Orthologous to human PIEZO1 (piezo type mechanosensitive ion channel component 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in lung adult (RPKM 39.8), ovary adult (RPKM 31.9) and 23 other tissues
Orthologs: human
Gene size: 69632bp
Exon count: 53