Full name: lysine demethylase 4A

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: JHDM3A; JMJD2; JMJD2A; TDRD14A

Summary: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. [provided by RefSeq, Apr 2009]

Expression: Ubiquitous expression in duodenum (RPKM 11.5), thyroid (RPKM 10.1) and 25 other tissues

Gene size: 55370bp

Exon count: 22