Kdm4a lysine (K)-specific demethylase 4A [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 230674)
Symbol: Kdm4a
Full name: lysine (K)-specific demethylase 4A
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: D4Ertd222e; JHDM3A; Jmjd2; Jmjd2a; mKIAA0677
Summary: Enables histone demethylase activity. Acts upstream of or within cardiac muscle hypertrophy in response to stress and negative regulation of histone H3-K9 trimethylation. Located in pericentric heterochromatin. Is expressed in several structures, including branchial arch; central nervous system; dorsal root ganglion; early conceptus; and genitourinary system. Orthologous to human KDM4A (lysine demethylase 4A). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 27.6), CNS E14 (RPKM 25.9) and 28 other tissues
Orthologs: human
Gene size: 43089bp
Exon count: 23