Full name: period circadian regulator 2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: FASPS; FASPS1

Summary: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders. [provided by RefSeq, Jan 2014]

Expression: Ubiquitous expression in testis (RPKM 8.7), gall bladder (RPKM 7.6) and 25 other tissues

Gene size: 56022bp

Exon count: 27