Full name: period circadian clock 2

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: mKIAA0347; mPer2

Summary: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by Clock/Arntl heterodimers but then represses this upregulation in a feedback loop using Per/Cry heterodimers to interact with Clock/Arntl. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders. [provided by RefSeq, Jan 2014]

Expression: Ubiquitous expression in adrenal adult (RPKM 15.3), bladder adult (RPKM 12.8) and 28 other tissues

Gene size: 43374bp

Exon count: 24