Full name: insulin receptor substrate 4

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CHNG9; IRS-4; PY160

Summary: IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.. [provided by RefSeq, Jul 2008]

Expression: Biased expression in ovary (RPKM 3.0), thyroid (RPKM 1.0) and 3 other tissues

Gene size: 16618bp

Exon count: 3