Full name: insulin receptor substrate 4

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: IRS-4

Summary: Predicted to enable insulin receptor binding activity and phosphatidylinositol 3-kinase binding activity. Predicted to be involved in insulin receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in cytosol and plasma membrane. Is expressed in several structures, including alimentary system; brain; branchial arch; eye; and genitourinary system. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 9. Orthologous to human IRS4 (insulin receptor substrate 4). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in CNS E18 (RPKM 1.0), testis adult (RPKM 0.8) and 8 other tissues

Gene size: 14220bp

Exon count: 2