Full name: NUF2 component of NDC80 kinetochore complex

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CDCA1; CT106; NUF2R

Summary: This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]

Expression: Biased expression in testis (RPKM 23.0), bone marrow (RPKM 9.4) and 11 other tissues

Gene size: 33806bp

Exon count: 15