Full name: NUF2, NDC80 kinetochore complex component

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 2410003C07Rik; Cdca1; NUF2R

Summary: Predicted to be involved in kinetochore organization; mitotic spindle organization; and nuclear division. Predicted to act upstream of or within attachment of spindle microtubules to kinetochore. Predicted to be located in cytosol; kinetochore; and nucleoplasm. Predicted to be part of Ndc80 complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in castration-resistant prostate carcinoma and pancreatic cancer. Orthologous to human NUF2 (NUF2 component of NDC80 kinetochore complex). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in CNS E11.5 (RPKM 19.6), liver E14 (RPKM 14.3) and 10 other tissues

Gene size: 33531bp

Exon count: 15