CDT1 chromatin licensing and DNA replication factor 1 [ Homo sapiens (human) ] - Gene - Data resources

81620

CDT1 chromatin licensing and DNA replication factor 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 81620)

Symbol: CDT1

Full name: chromatin licensing and DNA replication factor 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: DUP; RIS2

Summary: The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein. [provided by RefSeq, Mar 2011]

Expression: Biased expression in bone marrow (RPKM 13.5), placenta (RPKM 2.5) and 9 other tissues

Orthologs: mouse

Gene size: 5470bp

Exon count: 10