Cdt1 chromatin licensing and DNA replication factor 1 [ Mus musculus (house mouse) ] - Gene - Data resources

67177

Cdt1 chromatin licensing and DNA replication factor 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 67177)

Symbol: Cdt1

Full name: chromatin licensing and DNA replication factor 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 2610318F11Rik; DUP; Ris2

Summary: Enables DNA binding activity. Involved in DNA replication checkpoint signaling and regulation of DNA-dependent DNA replication initiation. Acts upstream of or within regulation of nuclear cell cycle DNA replication. Located in nucleus. Is expressed in adrenal medulla; brain ventricular layer; dorsal root ganglion; liver; and trunk mesenchyme derived from neural crest. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 4. Orthologous to human CDT1 (chromatin licensing and DNA replication factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in thymus adult (RPKM 48.2), liver E14.5 (RPKM 44.9) and 21 other tissues

Orthologs: human

Gene size: 5116bp

Exon count: 10