Full name: F-box protein 31

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: FBX14; FBXO14; Fbx31; MRT45; pp2386

Summary: This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Expression: Ubiquitous expression in fat (RPKM 13.6), ovary (RPKM 7.7) and 25 other tissues

Gene size: 65135bp

Exon count: 11