Full name: F-box protein 31

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 1110003O08Rik; 2310046N15Rik; Fbx14; Fbxo14

Summary: Predicted to enable cyclin binding activity. Predicted to be involved in several processes, including mitotic G1 DNA damage checkpoint signaling; positive regulation of dendrite morphogenesis; and proteasome-mediated ubiquitin-dependent protein catabolic process. Located in neuronal cell body. Is expressed in several structures, including adrenal gland; brain; early embryo; genitourinary system; and gut gland. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human FBXO31 (F-box protein 31). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in adrenal adult (RPKM 24.3), cortex adult (RPKM 21.5) and 28 other tissues

Gene size: 29426bp

Exon count: 10