Full name: THAP domain containing, apoptosis associated protein 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 4833431A01Rik

Summary: Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; protein homodimerization activity; and zinc ion binding activity. Predicted to be involved in several processes, including endothelial cell proliferation; negative regulation of transcription by RNA polymerase II; and transcription, DNA-templated. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be active in nucleus. Is expressed in forelimb bud and genitourinary system. Used to study torsion dystonia 6. Human ortholog(s) of this gene implicated in torsion dystonia 6. Orthologous to human THAP1 (THAP domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in testis adult (RPKM 5.6), CNS E11.5 (RPKM 3.2) and 28 other tissues

Gene size: 5983bp

Exon count: 3