THAP1 THAP domain containing 1 [ Homo sapiens (human) ] - Gene - Data resources

55145

THAP1 THAP domain containing 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 55145)

Symbol: THAP1

Full name: THAP domain containing 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: DYT6

Summary: The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links PAWR to PML nuclear bodies. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Expression: Ubiquitous expression in testis (RPKM 7.0), thyroid (RPKM 5.5) and 25 other tissues

Orthologs: mouse

Gene size: 6652bp

Exon count: 3