Vps11 VPS11, CORVET/HOPS core subunit [ Mus musculus (house mouse) ] - Gene - Data resources

71732

Vps11 VPS11, CORVET/HOPS core subunit [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 71732)

Symbol: Vps11

Full name: VPS11, CORVET/HOPS core subunit

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 1200011A11Rik

Summary: Predicted to enable several functions, including protein-macromolecule adaptor activity; syntaxin binding activity; and ubiquitin protein ligase activity. Acts upstream of or within toxin transport. Located in actin filament; early endosome; and presynaptic active zone. Part of AP-3 adaptor complex and CORVET complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 12. Orthologous to human VPS11 (VPS11 core subunit of CORVET and HOPS complexes). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in genital fat pad adult (RPKM 17.1), adrenal adult (RPKM 17.0) and 28 other tissues

Orthologs: human

Gene size: 13925bp

Exon count: 16