Full name: histone deacetylase 8

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 2610007D20Rik

Summary: Predicted to enable chromatin binding activity; heat shock protein binding activity; and histone deacetylase activity. Predicted to be involved in several processes, including histone deacetylation; negative regulation of macromolecule metabolic process; and regulation of chromosome organization. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of histone deacetylase complex. Is expressed in several structures, including 2-cell stage embryo; brain; embryo ectoderm; foregut; and retina. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 5 and Wilson-Turner syndrome. Orthologous to human HDAC8 (histone deacetylase 8). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in cerebellum adult (RPKM 1.2), bladder adult (RPKM 1.0) and 28 other tissues

Gene size: 220762bp

Exon count: 15