Cdk12 cyclin-dependent kinase 12 [ Mus musculus (house mouse) ] - Gene - Data resources

69131

Cdk12 cyclin-dependent kinase 12 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 69131)

Symbol: Cdk12

Full name: cyclin-dependent kinase 12

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 1810022J16Rik; Crk7; Crkrs; D11Ertd752e; Pksc

Summary: Enables protein kinase binding activity. Acts upstream of or within negative regulation of stem cell differentiation. Predicted to be located in nuclear speck. Predicted to be part of cyclin K-CDK12 complex and cyclin/CDK positive transcription elongation factor complex. Predicted to be active in nucleus. Is expressed in several structures, including blastocyst; early embryo; future brain; primitive streak; and unsegmented mesenchyme. Orthologous to human CDK12 (cyclin dependent kinase 12). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in CNS E11.5 (RPKM 3.5), limb E14.5 (RPKM 3.3) and 28 other tissues

Orthologs: human

Gene size: 78668bp

Exon count: 18