CDK12 cyclin dependent kinase 12 [ Homo sapiens (human) ] - Gene - Data resources

51755

CDK12 cyclin dependent kinase 12 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 51755)

Symbol: CDK12

Full name: cyclin dependent kinase 12

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CRK7; CRKR; CRKRS

Summary: Enables RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin binding activity. Involved in phosphorylation of RNA polymerase II C-terminal domain; protein autophosphorylation; and regulation of MAP kinase activity. Located in nuclear speck. Part of cyclin K-CDK12 complex. [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in testis (RPKM 8.6), bone marrow (RPKM 8.1) and 25 other tissues

Orthologs: mouse

Gene size: 106074bp

Exon count: 24