Full name: reticulon 4

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 1110020G17Rik; ASY; C130026I10Rik; NOGO; NSP-CL; NgA; Nogo-A; Nogo-B; Nogo-C; mKIAA0886; mKIAA4153

Summary: Predicted to enable cadherin binding activity; protein homodimerization activity; and ubiquitin protein ligase binding activity. Involved in several processes, including neurogenesis; positive regulation of leukocyte migration; and vasculogenesis. Acts upstream of or within blastocyst formation; circulatory system development; and regulation of cell growth. Located in several cellular components, including dendritic growth cone; neuronal cell body; and postsynaptic density. Is expressed in several structures, including central nervous system; genitourinary system; limb mesenchyme; sensory organ; and skeletal musculature. Orthologous to human RTN4 (reticulon 4). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in CNS E18 (RPKM 70.4), frontal lobe adult (RPKM 55.5) and 27 other tissues

Gene size: 51517bp

Exon count: 11