Full name: calsyntenin 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 1810034E21Rik; Cst-1; Cstn1

Summary: Predicted to enable X11-like protein binding activity; amyloid-beta binding activity; and kinesin binding activity. Involved in neurotransmitter receptor transport to postsynaptic membrane; regulation of synapse maturation; and vesicle-mediated transport in synapse. Acts upstream of or within positive regulation of synapse assembly; positive regulation of synaptic transmission; and regulation of cell growth. Located in several cellular components, including postsynaptic density; postsynaptic endosome; and postsynaptic membrane. Is integral component of membrane. Is active in glutamatergic synapse. Is expressed in central nervous system; intestine; and retina. Orthologous to human CLSTN1 (calsyntenin 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in cortex adult (RPKM 93.0), frontal lobe adult (RPKM 80.3) and 23 other tissues

Gene size: 62821bp

Exon count: 21