Full name: bleomycin hydrolase

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: BH; BMH

Summary: Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. [provided by RefSeq, Jul 2008]

Expression: Ubiquitous expression in skin (RPKM 54.6), placenta (RPKM 12.9) and 25 other tissues

Gene size: 43742bp

Exon count: 12