Full name: SEL1L adaptor subunit of ERAD E3 ubiquitin ligase

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: Hrd3; PRO1063; SEL1-LIKE; SEL1L1

Summary: The protein encoded by this gene is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol, where they are degraded by the proteasome in a ubiquitin-dependent manner. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Expression: Ubiquitous expression in pancreas (RPKM 48.9), thyroid (RPKM 38.9) and 25 other tissues

Gene size: 62307bp

Exon count: 21