Full name: dual specificity phosphatase 10

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 2610306G15Rik; MKP-5; MKP5

Summary: Enables MAP kinase phosphatase activity. Involved in several processes, including negative regulation of ERK1 and ERK2 cascade; negative regulation of epithelial cell migration; and negative regulation of epithelium regeneration. Acts upstream of or within several processes, including negative regulation of protein kinase activity; negative regulation of respiratory burst involved in inflammatory response; and oligodendrocyte differentiation. Predicted to be located in Golgi apparatus; cytosol; and nuclear speck. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human DUSP10 (dual specificity phosphatase 10). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in thymus adult (RPKM 37.9), testis adult (RPKM 13.3) and 21 other tissues

Gene size: 41259bp

Exon count: 7