BDKRB2 bradykinin receptor B2 [ Homo sapiens (human) ] - Gene - Data resources

624

BDKRB2 bradykinin receptor B2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 624)

Symbol: BDKRB2

Full name: bradykinin receptor B2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: B2R; BK-2; BK2; BKR2; BRB2

Summary: This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. Bradykinin is released upon activation by pathophysiologic conditions such as trauma and inflammation, and binds to its kinin receptors, B1 and B2. The B2 receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. [provided by RefSeq, Apr 2020]

Expression: Broad expression in urinary bladder (RPKM 13.5), gall bladder (RPKM 13.3) and 16 other tissues

Orthologs: mouse

Gene size: 39326bp

Exon count: 3