Full name: isoprenylcysteine carboxyl methyltransferase

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 1700008E11Rik; Gm13095; HSTE14; PPMT; STE14; pcCMT

Summary: Enables cAMP response element binding protein binding activity and protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity. Acts upstream of or within several processes, including TOR signaling; bone mineralization; and determination of adult lifespan. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human ICMT (isoprenylcysteine carboxyl methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in cerebellum adult (RPKM 44.7), adrenal adult (RPKM 31.6) and 28 other tissues

Gene size: 9913bp

Exon count: 6