ICMT isoprenylcysteine carboxyl methyltransferase [ Homo sapiens (human) ]
Source: NCBI Gene (ID 23463)
Symbol: ICMT
Full name: isoprenylcysteine carboxyl methyltransferase
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: HSTE14; MST098; MSTP098; PCCMT; PCMT; PPMT
Summary: This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. [provided by RefSeq, Jul 2008]
Expression: Ubiquitous expression in kidney (RPKM 21.7), placenta (RPKM 18.3) and 25 other tissues
Orthologs: mouse
Gene size: 14772bp
Exon count: 6