Full name: programmed cell death 10

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 2410003B13Rik; Ccm3; Tfa15; Tfar15

Summary: Predicted to enable protein N-terminus binding activity; protein homodimerization activity; and protein kinase binding activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in cytosol. Predicted to be part of FAR/SIN/STRIPAK complex. Predicted to be active in Golgi apparatus. Is expressed in several structures, including cardiovascular system; central nervous system; gut; retina layer; and umbilical artery. Used to study cerebral cavernous malformation 3. Human ortholog(s) of this gene implicated in cerebral cavernous malformation 3. Orthologous to human PDCD10 (programmed cell death 10). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in placenta adult (RPKM 13.4), bladder adult (RPKM 12.3) and 20 other tissues

Gene size: 40363bp

Exon count: 8