Full name: A kinase (PRKA) anchor protein 8

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: 1200016A02Rik; AKAP-8; AKAP95

Summary: This gene encodes a member of the A-kinase anchoring protein (AKAP) family. These proteins are characterized by their ability to bind to the R subunit of protein kinase A (PKA) and anchor the protein at different subcellular locations. This protein has been shown to regulate apoptosis and to be involved in palatogenesis. Knockdown of this gene has been associated with altered histone modifications and reduced expression of developmental genes in mouse embryonic stem cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]

Expression: Ubiquitous expression in CNS E11.5 (RPKM 24.6), CNS E14 (RPKM 20.6) and 28 other tissues

Gene size: 17567bp

Exon count: 16