AKAP8 A-kinase anchoring protein 8 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 10270)
Symbol: AKAP8
Full name: A-kinase anchoring protein 8
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: AKAP 95; AKAP-8; AKAP-95; AKAP95
Summary: This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011]
Expression: Ubiquitous expression in bone marrow (RPKM 13.0), spleen (RPKM 9.2) and 25 other tissues
Orthologs: mouse
Gene size: 26403bp
Exon count: 14