TET2 tet methylcytosine dioxygenase 2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 54790)
Source: NCBI Gene (ID 54790)
Symbol: TET2
Full name: tet methylcytosine dioxygenase 2
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: IMD75; KIAA1546; MDS
Summary: The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Expression: Ubiquitous expression in bone marrow (RPKM 5.5), appendix (RPKM 4.6) and 25 other tissues
Orthologs: mouse
Gene size: 133929bp
Exon count: 14